Oxygen Microbubbles (OMBs) – Stabilized oxygen gas spheres delivered sterile to the physician. Every cell in the body requires oxygen to maintain correct homeostasis, and hypoxic conditions can quickly lead to irreversible organ damage or death. OMB technology has demonstrated the ability to deliver oxygen to the blood stream independent of the lungs.
Tight control of the size and composition allows for microbubbles to provide systemic oxygenation to patients with lung compromise. OMB are well characterized, stable, easy to transport, and inexpensive to produce. Phospholipids are the building blocks of cell membranes and are used to enhance drug safety.
Peritoneal oxygenation - oxygen uptake without the lungs - has been validated in vivo in a small animal model.
OMB delivered via the peritoneum allows 100% survival to 2 hours. Control survival was less than 30 minutes.
Research is continuing with the University of Nebraska and University of Colorado, supported by United States Air Force research grants
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